{"id":1649,"date":"2017-07-27T08:05:35","date_gmt":"2017-07-27T12:05:35","guid":{"rendered":"https:\/\/www.roshreview.com\/?p=1649"},"modified":"2024-02-21T17:09:07","modified_gmt":"2024-02-21T17:09:07","slug":"rapid-review-cushings-syndrome","status":"publish","type":"post","link":"https:\/\/www.roshreview.com\/blog\/rapid-review-cushings-syndrome\/","title":{"rendered":"Rapid Review: Cushing Syndrome"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em>Reviewed February 2024<\/em><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"694\" height=\"1024\" src=\"https:\/\/www.roshreview.com\/blog\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-694x1024.png\" alt=\"\" class=\"wp-image-13393\" srcset=\"https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-694x1024.png 694w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-203x300.png 203w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-768x1134.png 768w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-1041x1536.png 1041w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Cushing-Disease-Cushing-Syndrome-@8x-1387x2048.png 1387w\" sizes=\"auto, (max-width: 694px) 100vw, 694px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Cushing Syndrome<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Patient presents with <strong>amenorrhea<\/strong>, <strong>central obesity<\/strong>, <strong>depressive symptoms<\/strong>, and<strong> easy bruising<\/strong><\/li>\n\n\n\n<li>PE: <strong>purple striae<\/strong>, <strong>moon face<\/strong> (facial adiposity), <strong>buffalo hump<\/strong> (increased adipose tissue in the neck and upper back), and <strong>hypertension<\/strong><\/li>\n\n\n\n<li>Diagnosis: 24-hour urinary free cortisol, late night salivary cortisol, dexamethasone suppression test, ACTH levels<\/li>\n\n\n\n<li>Most common <strong>noniatrogenic <\/strong>cause is <strong>hypercortisolism from ACTH-secreting pituitary tumor<\/strong><\/li>\n\n\n\n<li>If cause is pituitary tumor then it&#8217;s called <strong>Cushing disease<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><span style=\"text-decoration: underline;\"><strong>Sample question:<\/strong><\/span><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A 35-year-old woman presents to the clinic with decreased libido, <strong>weight gain<\/strong>, and <strong>menstrual irregularities<\/strong>. She says she has gained 35 pounds in the past three months without any changes in her diet. She has also noticed her f<strong>ace has become more round<\/strong>. Examination shows a <strong>dorsal fat pad<\/strong>, <strong>hirsutism<\/strong>, and purplish <strong>abdominal<\/strong> <strong>striae<\/strong>. Which of the following is the most likely diagnosis?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reviewed February 2024 Cushing Syndrome Sample question: A 35-year-old woman presents to the clinic with decreased libido, weight gain, and menstrual irregularities. She says she has gained 35 pounds in the past three months without any changes in her diet. She has also noticed her face has become more round. Examination shows a dorsal fat <a href=\"https:\/\/www.roshreview.com\/blog\/rapid-review-cushings-syndrome\/\">read more&#8230;<\/a><\/p>\n","protected":false},"author":15,"featured_media":6906,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[2020,1996,2021,2022,2023,2024,2025,2026,2027,2028,2029,2010,2000],"tags":[2594,3203,3215],"coauthors":[3864],"class_list":["post-1649","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-adult-gerontology-primary-care","category-blogtype","category-pa-certified","category-certified-emergency-nurse","category-clinical-year","category-didactic-year","category-emergency-medicine","category-emergency-nurse-practitioner","category-family-medicine","category-family-nurse-practitioner","category-internal-medicine","category-ob-gyn","category-rapid-review","tag-endocrine","tag-pance","tag-panre"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.7 (Yoast SEO v26.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Rapid Review: Cushing Syndrome - RoshReview.com<\/title>\n<meta name=\"description\" content=\"This Rapid Review distills the important facts about Cushing\u2019s syndrome, so you can brush up your knowledge and be a confident medical professional. 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