{"id":1678,"date":"2017-09-04T07:43:15","date_gmt":"2017-09-04T11:43:15","guid":{"rendered":"https:\/\/www.roshreview.com\/?p=1678"},"modified":"2024-02-02T21:58:27","modified_gmt":"2024-02-02T21:58:27","slug":"rapid-review-polycystic-ovarian-syndrome","status":"publish","type":"post","link":"https:\/\/www.roshreview.com\/blog\/rapid-review-polycystic-ovarian-syndrome\/","title":{"rendered":"Rapid Review: Polycystic Ovarian Syndrome"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em>Reviewed February 2024<\/em><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"631\" height=\"1024\" src=\"https:\/\/www.roshreview.com\/blog\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-631x1024.png\" alt=\"\" class=\"wp-image-13354\" srcset=\"https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-631x1024.png 631w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-185x300.png 185w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-768x1246.png 768w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-947x1536.png 947w, https:\/\/www.roshreview.com\/wp-content\/uploads\/sites\/2\/2024\/02\/Image-Polycystic-Ovary-Syndrome-PCOS-in-Adolescents-@8x-1-1263x2048.png 1263w\" sizes=\"auto, (max-width: 631px) 100vw, 631px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Polycystic Ovary Syndrome (PCOS)<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Ovulatory dysfunction<\/strong>,<strong> hyperandrogenism<\/strong>, and <strong>polycystic ovaries<\/strong><\/li>\n\n\n\n<li>Common PE findings: bilateral ovarian enlargement, acanthosis nigricans, high BMI<\/li>\n\n\n\n<li>Laboratory evaluation:\n<ul class=\"wp-block-list\">\n<li>Oligomenorrhea: hCG, FSH, TSH, prolactin<\/li>\n\n\n\n<li>Hyperandrogenism: total testosterone and sex hormone-binding globulin or bioavailable and free testosterone, morning 17-hydroxyprogesterone<\/li>\n\n\n\n<li>Metabolic disease screening: 2-hour oral glucose tolerance test, fasting lipid panel<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Commonly associated with <strong>insulin resistance<\/strong>,<strong> <\/strong>which may be the central etiology<\/li>\n\n\n\n<li>Treatment is combination low-dose <strong>oral contraceptive pills<\/strong>, <strong>lifestyle changes<\/strong>, <strong>metformin<\/strong><\/li>\n\n\n\n<li><strong>Most common cause of infertility<\/strong> and warrants <strong>ovulation induction<\/strong>:\n<ul class=\"wp-block-list\">\n<li><strong>Clomiphene citrate <\/strong>traditionally first-line, FDA-approved<\/li>\n\n\n\n<li><strong>Letrozole<\/strong> increasingly preferred therapy (off-label)<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><span style=\"text-decoration: underline;\">Sample question:<\/span><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A 28-year-old woman presents to the physician because she and her partner have been <strong>trying to conceive for the past year without success<\/strong>. She reports <strong>irregular menstrual periods<\/strong>, with cycles ranging from 20 to 50 days apart. Physical examination reveals <strong>acne and hirsutism<\/strong>. Her <strong>body mass index is 32 kg\/m<sup>2<\/sup><\/strong>. Laboratory studies show an increased luteinizing hormone to follicle-stimulating hormone ratio. Which of the following best describes the underlying pathophysiology of this patient\u2019s condition?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reviewed February 2024 Polycystic Ovary Syndrome (PCOS) Sample question: A 28-year-old woman presents to the physician because she and her partner have been trying to conceive for the past year without success. She reports irregular menstrual periods, with cycles ranging from 20 to 50 days apart. Physical examination reveals acne and hirsutism. Her body mass <a href=\"https:\/\/www.roshreview.com\/blog\/rapid-review-polycystic-ovarian-syndrome\/\">read more&#8230;<\/a><\/p>\n","protected":false},"author":15,"featured_media":6906,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[2020,1996,2021,2022,2023,2024,2025,2026,2027,2028,2029,2010,2011,2000],"tags":[3203,3215,3245,3453],"coauthors":[3864],"class_list":["post-1678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-adult-gerontology-primary-care","category-blogtype","category-pa-certified","category-certified-emergency-nurse","category-clinical-year","category-didactic-year","category-emergency-medicine","category-emergency-nurse-practitioner","category-family-medicine","category-family-nurse-practitioner","category-internal-medicine","category-ob-gyn","category-pediatric-emergency-medicine","category-rapid-review","tag-pance","tag-panre","tag-pcos","tag-reproductive"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.7 (Yoast SEO v26.6) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Rapid Review: Polycystic Ovarian Syndrome - RoshReview.com<\/title>\n<meta name=\"description\" content=\"This Rapid Review distills the important facts about polycystic ovarian syndrome, so you can brush up your knowledge and be a confident medical professional. 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