Rapid Review: Kawasaki Disease

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August 14, 2017

Reviewed February 2024

Kawasaki Disease

  • Children < 5 years old
  • History of high fever × 5 days
  • Conjunctivitis, rash, adenopathy, strawberry tongue, hand or foot edema, fever
  • Leading cause of pediatric acquired heart disease, risk for coronary artery aneurysm
  • CRASH and burn: conjunctivitis, rash, adenopathy, strawberry tongue, hand or foot edema, uncontrolled high fever
  • Tx: IVIG + aspirin

Sample question:

A 4-year-old boy presents to the emergency department with his parents because of a rash and fever for 7 days. His temperature is 102.9°F (39.4°C) and heart rate is 120 bpm. Physical examination demonstrates bilateral conjunctival injection, an erythematous tongue, and anterior cervical lymphadenopathy. The patient has a maculopapular rash involving the trunk, hands, and feet. Which of the following is the most likely cause of these symptoms?

By Yehuda Wolf, MPA, PA-C


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