Rapid Review: Megaloblastic Anemia
Megaloblastic Anemia
- Patient will be a vegan or alcoholic
- Complaining of fatigue, weakness
- PE will show pallor, glossitis
- Labs will show MCV > 100 and hypersegmented neutrophils
- Most commonly caused by vitamin B12 (Cobalamin) or folate deficiency
- Comments: only vitamin B12 deficiency results in neurological symptoms
Sample question:
A middle-aged patient in the ED has a hemoglobin of 8.1 g/dL with an MCV of 112 fL. Which of the following is a common cause of this disease process?
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