Rapid Review: Multiple Myeloma

June 15, 2017
Multiple myeloma

Multiple Myeloma

  • Patient will be elderly
  • Complaining of back pain
  • PE will show CRAB: hyperCalcemia, Renal insufficiency, Anemia, lytic Bone lesions/Back pain
  • Labs will show monoclonal antibody spike
  • X-ray will show lytic lesions
  • Peripheral blood smear: Rouleaux formations
  • Serum protein electrophoresis: M spike
  • Protein electrophoresis urine analysis: Bence-Jones proteins
  • Most commonly caused by single clone plasma cell malignancy

By Yehuda Wolf, MPA, PA-C

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