Rapid Review: von Willebrand Disease

July 6, 2017
von Willebrand disease

von Willebrand Disease

  • Patient with a history of a parent with similar symptoms
  • Mucosal hemorrhage or bleeding that is difficult to control
  • Labs will show decreased factor VIII, prolonged bleeding time
  • Treatment is desmopressin (DDAVP)
  • Comments: Most common inherited bleeding disorder, autosomal dominant

Sample question: A 9-year-old child is being evaluated for frequent epistaxis and easy bruising tendencies. Bleeding time is prolonged, PT, PTT, and INR are within normal limits. What is the most likely diagnosis?

By Yehuda Wolf, MPA, PA-C

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