Rapid Review: Ankylosing Spondylitis

July 10, 2017
Ankylosing spondylitis

Ankylosing Spondylitis

  • Patient will be a male
  • Complaining of low back pain that’s worse in the morning and improves with exercise
  • X-ray will show multiple vertebral fusions (bamboo spine)
  • Labs will show increased ESR
  • Most commonly caused by presence of HLA-B27
  • Treatment is NSAIDs, physical therapy
  • Comments: diseases associated with HLA-B27
    • PAIRPsoriatic arthritis, Ankylosing spondylitis, Inflammatory bowel disease, Reactive arthritis

Sample question: A 51-year-old man presents with low back pain that has been worsening over the past several years. Radiographs of the spine demonstrate fusion of the sacroiliac joints and a bamboo spine.” Blood tests reveal that he is human leukocyte antigen B27 positive. Which of the following findings on physical exam would be most consistent with the suspected diagnosis?

By Yehuda Wolf, MPA, PA-C

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