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Physician Assistant Review Questions

Just like you’ll see on the PANRE exams

No “negatively phrased” questions, no “all of the following except”, no “A and B”…you know what we mean. In order for a test question to be high quality, it must satisfy two basic criteria:

  1. Must address important content
  2. Must be well structured
Question » Stem » Lead in

A 67-year-old woman who was recently diagnosed with breast cancer presents with increasing confusion over the past three days. Additionally, over the past week she has been complaining of fatigue, diffuse body aches, poorly localized abdominal pain, and constipation. Which of the following electrolyte abnormalities is the most likely explanation for her symptoms?

Our Answer Choices

Building difficulty into the question. Meet the Challenge.

A question’s difficulty is defined by the choice of distractors. Good distractors determine the difficulty level of a question. Therefore, good distractors are one of the most important features of a high quality question.


Understanding why an answer choice is incorrect is just as important as knowing why it is correct

Our Explanations

Synthesized for optimized learning and recall & created with a purpose

Every question contains a detailed explanation for the correct and incorrect answer choices and integrated media for those that learn best by visual stimuli Understanding a topic cannot be learned in isolation. You require context. We take deliberate steps to deliver a comprehensive explanation linking the most important components to master a topic.

The patient has hypercalcemia of malignancy. Total body calcium levels are tightly regulated by a feedback loop in which parathyroid hormone induces the bones and kidneys to increase serum calcium levels. Conversely, elevated calcium levels inhibit parathyroid hormone release. Vitamin D also plays a role in regulating calcium absorption in the gut. Hypercalcemia is defined as a serum calcium > 10.5 mg/dL. Symptoms of hypercalcemia are varied and include non-focal abdominal pain, constipation, fatigue, diffuse myalgias, anorexia, nausea, and vomiting. Neuropsychiatric manifestations such as depression, anxiety, and hallucinations may also be seen. Severe cases may lead to altered mental status, seizures, and coma. The mnemonic “moans, groans, stones, and psychic overtones,” is useful for remembering hypercalcemia, including the above manifestations as well as a predilection for forming kidney stones. Hypercalcemia has numerous causes, including primary hyperparathyroidism, hyperthyroidism, multiple myeloma, cancer metastatic to bone, granulomatous disease (e.g. sarcoidosis). Medications, such as thiazide diuretics and estrogens, can also raise serum calcium levels. In this elderly patient with a recent diagnosis of breast cancer, bony metastases is a likely cause of hypercalcemia. Hypercalcemia is initially managed with fluids and forced calciuresis. Intravenous saline is needed in severe cases. Intravenous bisphosphonates may be used in hypercalcemia that is due to hyperparathyroidism or a malignancy. Calcitonin can be given to manage hypercalcemia while the bisphosphonates reach therapeutic levels. Unmanaged hypercalcemia may lead to serious complications including neuromuscular manifestations such as weakness or paresthesia, or cardiac arrhythmias secondary to QT interval shortening or heart block.

Enhanced Learning

Explanations contain integrated audio and visual content to further clarify meaning of the core concept. By representing information using audio cues and spatially with images, you are able to focus on meaning, reorganize and group similar ideas easily and make better use of your audio and visual memory.

More than just a question

Advanced reinforcement

To optimize recall and understanding of a topic we link concepts to help you express knowledge, thoughts and ideas and build relationships between them.


Taking Your Learning One Step Further

After each question explanation is a straightforward factoid-based questions with a simple, memorizable answer that serves as reinforcement for the corresponding topic.

(Q) What is a classic ECG finding of hypercalcemia?

(A) Shortened QT interval.


Cutting edge, staying up to date

Gain a deeper understanding by linking standard board material with cutting edge clinical knowledge

Shigella sonnei bacteria resistant
Shigella sonnei bacteria resistant to the antibiotic ciprofloxacin sickened 243 people in 32 states and Puerto Rico between May 2014 and February 2015. In the United States, most Shigella is already resistant to the antibiotics ampicillin and trimethoprim/sulfamethoxazole. Because Cipro-resistant Shigella is spreading, CDC recommends doctors use lab tests to determine which antibiotics will effectively treat shigellosis. Doctors and patients should consider carefully whether an infection requires antibiotics at all.


Break it down, Keep it simple.

Boiling it down to the most high yield concepts


  • Malignancy (most common inpatient cause)
  • Primary hyperparathyroidism (most common outpatient cause)
  • Bones, stones, groans, psychiatric overtones
  • ↓ QT interval Initial rx: IVF

Powerful Analytics

Progress, performance, predictions

“If you can’t measure it, you can’t manage it.” Rosh Review provides you with key statistics and robust analytics to create an efficient and effective learning strategy


Focus your learning on what matters

Identify your strengths and weaknesses based on the NCCPA Content Blueprint.

Peer comparison

Compare your answer choices to the answers provided by other students and physician assistants around the country.

Probability of Passing Your Exam

Using data generated by our previous users, we can predict your probability of passing the PANRE.

“I just passed my PANRE exam for the 7th time with the help of Rosh Review!!!! I am 63-years-old and have practiced as a Family Practice PA for 26 years, and for the past 11 years as a Neurology PA—for a total of 37 years. I have been out of Primary Care for the last 11 years, and have got to say—-a lot of general medicine had been forgotten. I took the PANRE in August and failed (even though I studied another print guide for 2 months). I then started using Rosh Review in mid Sept. and passed the PANRE Dec 3rd. I reviewed over 1800 questions and found the explanations and pictures to be very helpful. The One Step Further questions and Rapid Review were very helpful as well. Thank you so much for a GREAT web based review—I learned so much more.”

Wallace Green, PA-C

Physician Assistant Question Topics

The NCCPA publishes a Content Blueprint for the material that will appear on your exam. This blueprint is how we determine which material appears in your Qbank. Blueprints are always updated with the latest version released by the NCCPA.

Eyes, Ears, Nose, and Throat8%
Neurologic System7%
Infectious Diseases6%

Specialty Certificates

Certificate of Added Qualifications (CAQ). Content created specifically for the CAQ exam.

According to the NCCPA:

  • Over 75% found or anticipate finding a new job
  • Over 40% successfully sought a promotion
  • 60% achieved or expect to increase their job responsibilities
  • Over 50% received or anticipate received a pay increase
  • 33% received a cash bonus
  • Over 75% found the CAQ useful in documenting qualifications required for external accreditation
  • Over 33% achieved or anticipate a broadening of their eligibility for reimbursement
  • Almost 75% have received greater recognition or regard from physicians or other health care professionals
  • 66% reported greater respect or acceptance from patients

Continuing Medical Education

Self Assessment

Satisfy your Self Assessment NCCPA Certification Maintenance requirement.

Earn and Learn

Complete the Self Assessment Qbank and Earn 20 AAPA Category 1 CME Credits



Interested in group subscriptions for 10 or more? Learn More

Crush your PANRE & earn CME


1 year
$349 - 90 days / $329 - 30 days

Pass Guaranteed. Period.

**Updated 2019 NCCPA Blueprint**

3,000 NCCPA-formatted questions

3,000 Comprehensive explanations

3,000 One Step Further questions and answers

Includes 100 AMA PRA Cat 1 CME credit(s)™

Alternative PANRE
ACE the ALT and earn CME


2 years
$299 - 1 year

Pass Guaranteed. Period.

**Updated 2019 NCCPA Blueprint**

Every Alternative PANRE topic covered

600 NCCPA-formatted questions

600 Comprehensive explanations

600 One Step Further questions and answers

Includes 60 AMA PRA Cat 1 CME credit(s)™

Emergency Medicine CAQ
Rock your CAQ & Earn CME


1 year
$349 - 3 months
$329 - 1 month

Pass Guaranteed. Period.

Matches NCCPA EM CAQ Blueprint

1,500 NCCPA-formatted questions

1,500 Comprehensive explanations

1,500 One Step Further questions and answers

Includes 100 AMA PRA Cat 1 CME credit(s)™

Pediatric CAQ
Rock your CAQ & Earn CME


1 year
$349 - 3 months
$329 - 1 month

Pass Guaranteed. Period.

Matches NCCPA Pediatrics CAQ Blueprint

900 NCCPA-formatted questions

900 Comprehensive explanations

900 One Step Further questions and answers

Includes 100 AMA PRA Cat 1 CME credit(s)™

Hospital Medicine CAQ
Rock your CAQ & Earn CME


1 year
$349 - 3 months
$329 - 1 month

Pass Guaranteed. Period.

Matches NCCPA Hospital Medicine CAQ Blueprint

1,100 NCCPA-formatted questions

1,100 Comprehensive explanations

1,100 One Step Further questions and answers

Includes 100 AMA PRA Cat 1 CME credit(s)™

Self Assessment -
General PA
General Practice CME


1 year

Satisfy NCCPA Certification Maintenance requirement

400 NCCPA-formatted questions and answers

20 AAPA Category 1 Self-Assessment CME credits

Self Assessment - <br />General PA
Self Assessment -
Emergency Medicine
Emergency Medicine CME


1 year

Satisfy NCCPA Certification Maintenance requirement

400 NCCPA-formatted questions and answers

20 AAPA Category 1 Self-Assessment CME credits

Self Assessment - <br />Emergency Medicine

Easy-to-Use Testing

We create high quality educational content, perform assessment and analytics for individuals and organizations and deliver it through an easy-to-use web-based interface.

Creating Human Connections

See what motivates us to keep working hard for you.